Literature Highlight: Preventing Recurrent Venous Thromboembolism with Low-Dose Aspirin
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چکیده
Unprovoked venous thromboembolism (VTE) warrants anticoagulant therapy for a brief period of weeks to months. After it is discontinued, the risk of recurrent VTE remains high. Long-term warfarin therapy is highly effective in preventing recurrence, but it has an increased risk of bleeding, and the monitoring requirements make it inconvenient and costly for patients. Low-dose aspirin is a proposed alternative that is both inexpensive and convenient for patients.
منابع مشابه
Low-dose aspirin for preventing recurrent venous thromboembolism.
BACKGROUND Patients who have had a first episode of unprovoked venous thromboembolism have a high risk of recurrence after anticoagulants are discontinued. Aspirin may be effective in preventing a recurrence of venous thromboembolism. METHODS We randomly assigned 822 patients who had completed initial anticoagulant therapy after a first episode of unprovoked venous thromboembolism to receive ...
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Low-dose heparin, dipyridamole (alone and in combination with aspirin), and flurbiprofen were evaluated as potential prophylactic agents against deep venous thrombosis in elderly patients with hip fractures. None of the agents that modify platelet behaviour could reduct the frequency of isotopically diagnosed venous thrombosis. Low-dose heparin reduced the overall frequency of venous thrombosis...
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Patients with provoked venous thromboembolism caused by transient risk factors can generally stop anticoagulation after 3 months of treatment. For patients with unprovoked venous thromboembolism, for which the risk of recurrence is as high as 40% at 5 years,1 it may be appropriate to consider a longer course of therapy. However, deciding how to balance the risks and benefits of extended anticoa...
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A prospective study of patients undergoing total knee replacement was carried out by using a combination of 125I-fibrinogen scanning and phlebography, and showed a high incidence of venous thromboembolic disease (TE). Ventilation-perfusion lung scanning was performed to detect pulmonary emboli in most patients. High doses of aspirin and an intermittent low-pressure pneumatic compression device ...
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